Numerous over-the-counter medications can help relieve the symptoms of pityriasis rosea. A 1% hydrocortisone cream can be applied to small, itchy spots. It should only be used on sensitive areas such as the face or genitals sparingly and not at all for children younger than 12 years old. Hydrocortisone cream should not be given to toddlers under two years of age. Antihistamines can also help. Although this allergy medicine is available as an over-the-counter drug, check with your doctor before giving it to a child. Depending on the severity of the rash and its symptoms, a medical provider may prescribe an antiviral drug.

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