Although bulbous pemphigoid is rare, it tends to occur more often in older individuals, over 60. The risk of contracting this condition increases as you age, and is thought to be linked to a lower functioning immune system. Your body's immune system may produce antibodies that trigger the inflammation that causes bullous pemphigoid blisters.
Those with an already compromised immune system, whether from a pre-existing condition or as a side effect of some medications. If you know that you have a lower functioning immune system, or if you begin a medicine regimen that affects your immune function, consult about risk factors with your doctor and pay close attention to your skin.

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