Another genetic disorder that ican cause random bruising is Ehlers-Danlos syndrome or EDS. EDS weakens the connective tissues of skin, bones, and other organs, as well as blood vessels and muscles, leaving them unstable and loose. As a result of this fragility, extensive bruising and spontaneous ruptures that cause severe internal bleeding are risks in all subtypes of the disease. Doctors must monitor clotting factors and platelets in people with EDS. Treatments include surgery and pain-relieving drugs.

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