Understanding Random Bruising: 10 Possible Medical Reasons

10. von Willebrand Disease

Many with von Willebrand disease inherit it through a faulty gene from their parents, while others acquire it as a secondary condition without a parental connection. The usual cause is low levels of von Willebrand factor, a protein that helps platelets stick together properly. Additional causes include reduced amounts of factor VIII, which typically stimulates clotting. Treatment depends on the subtype of the disease and includes concentrated doses of those clotting factors and the use of a synthetic hormone to control bleeding.