Like dry gangrene, people with gas gangrene may not notice at first, as the skin can remain unblemished. This version of gangrene causes gas to develop in deep muscle tissue. Over time, the skin will begin to change color and may appear bubbly and make a crackling sound when you press on it. The most common cause of gas gangrene is the Clostridium perfringens bacterium, which tends to be contracted through surgical wounds. Toxins from the bacteria release gas, destroy tissue, and can lead to death.

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