Some self-care measures will reduce the risk of developing gangrene. People with diabetes should watch for cuts, sores, and infection, and control their blood sugar. Other preventive measures include avoiding tobacco products and maintaining a healthy weight. It is also helpful for people who are at risk for gangrene to keep a close watch on their skin during cold weather. Frostbite, which leaves the skin cold, numb, pale, and hard, can lead to gangrene.

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