Antibiotics often cause SJS. Nearly 200 medications are known to create this immune reaction. Those used for arthritis and gout are common culprits. Also, certain antibiotics prescribed to fight infection can lead to this condition. Medicines that treat mental illness and seizures can also cause SJS, as can over-the-counter painkillers. Susceptibility to SJS can also be increased if you have certain hereditary markers, have undergone radiation, or previously had SJS. People who are HIV-positive or have another immune disorder are also at higher risk. SJS can occur in both children and adults and can be life-threatening.
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