Pulmonary hypertension increases the pressure in the arteries and veins that supply the lungs with oxygenated blood and carry deoxygenated blood away. Multiple factors can cause it, including left-sided heart disease, lung disease, hypoxia, clots, or damage to the alveoli.
Pressure builds inside the lungs' blood vessels until the right ventricle of the heart can no longer sustain cardiac output. The most common cause of death in people with pulmonary hypertension is right-sided heart failure.

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