Occasionally, disease-causing bacteria and microorganisms can spread from the blood to a joint. This may also be referred to as a joint infection. The infection causes inflammation in the affected joint, as well as pain and stiffness. Fever, headaches, and general weakness can accompany these initial symptoms. Artificial joints and chronic illnesses such as diabetes or rheumatoid arthritis are the leading risk factors for a joint infection. The infection can be lethal if the individual does not seek treatment quickly.

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