10 Causes of Pulmonary Arterial Hypertension

2. Certain drugs

Prolonged use of drugs such as cocaine and amphetamines can cause pulmonary arterial hypertension. Specific weight loss drugs, which are no longer used in the medical weight loss profession in the last decade, were commonly used in the 1990s were also a culprit of the onset of PAH, however. Other over-the-counter pain medications, known as NSAIDs (non-steroidal Anti-inflammatory pain medications), can also contribute to pulmonary arterial hypertension symptoms if used too regularly. These drugs include ibuprofen, naproxen, and Etodolac celecoxib. These medications can put pressure on the kidneys, promote fluid retention and worsen any kidney problem that may already exist.