The lesion is located in the post-chiasmal part of the visual pathway, and the affected individual will not be able to perceive either the right half or the left half of the visual world of each eye.
It is estimated that 70% of the injuries leading to this type of loss are due to an obstruction of the blood supply (stroke) along the optic tract and brain structures such as the lateral geniculate body and the occipital lobe of the cerebral hemisphere. The affected population will more likely have diseases that affect the circulatory system such as arterial hypertension and diabetes. However, any disorder that affects the brain, including tumors, inflammation, and injuries can lead to homonymous hemianopia.

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