The most serious blood vessel that high cholesterol can target is the aorta. The aorta is the central artery that carries blood to the rest of the body. If it begins to narrow or harden, this can cause the aortic walls to bulge outward, which can lead to an aortic aneurysm.
Aortic aneurysms are typically treated with surgery. If they go untreated, however, they may eventually rupture and can be fatal.

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