Under normal circumstances, dealing with dead cells involves enzymes that break down proteins into recyclable amino acids. When coagulative necrosis occurs, something alters the natural qualities of these proteins. Albumin, for example, becomes a firm and opaque gel that remains in dead tissues. This type of necrosis is usually caused by severe ischemia in tissues of the adrenal glands, kidney or heart. In most cases, labile cells -- cells that constantly multiply -- replace dead cells. The exceptions are neurons and cardiomyocytes, which the body cannot replace once lost.

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