Chamomile and honey are popular natural options for treating many health conditions and the combination can be effective in reducing pain and inflammation associated with canker sores. Honey can be applied directly to a canker sore, thanks to its antiseptic properties. You can also stir it into chamomile tea for a similar effect. Chamomile has anti-inflammatory properties that address a primary issue of canker sores. Brew a cup of chamomile tea and use it as a rinse or soak a tea bag in warm water and apply it directly to the canker sore.

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