Between the ages of 1 and 4, children with Rett Syndrome typically lose the use of their hands. They may also develop other habitual hand movements, often associated with other autistic conditions, such as hand-wringing or hand washing, clapping, tapping or clasping. This phase of the condition can continue long into the teens. These physical manifestations may improve slightly over time but will be with the patient for the remainder of their life.

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