10 Facts About Spleen Pain You Need to Know

8. Other Causes of Spleen Pain

Certain prescription drugs may cause damage and spleen pain. All drugs have potential adverse effects, and some can be toxic to certain organs, interfering with their natural processes. Some can cause hemolysis in the spleen, which is a rupturing of red blood cells. However, once the individual stops taking the medication, the spleen pain usually goes away. Liver diseases, such as cirrhosis, can cause spleen pain as well. Cirrhosis of the liver also increases the blood pressure inside the spleen’s vessels, causing it to become enlarged, which leads to pain.