Although most spleen ruptures occur as the result of blunt force, spontaneous spleen ruptures are also possible. Infections or illnesses such as pneumonia, mononucleosis, and pulmonary infections may cause this type of rupture. Spontaneous ruptures also occur as a result of abnormal benign or malignant growths called neoplasias. The sudden onset of severe pain in the abdomen and left shoulder, especially from those already fighting off an infection, could indicate a spontaneous spleen rupture.

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