One of the leading causes of death in Irish wolfhounds is bone cancer. Some of the symptoms include limping or a lump on one of the legs. Because these courageous dogs seldom show signs of pain, cancer may go undetected and spread to the lungs. Lymphoma is another malignancy vets diagnose in this breed. Early signs are extreme fatigue, a lowered appetite, and, later, enlarged lymph nodes. Chemotherapy is an option.

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