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6. Rhabdomyolysis

Rhabdomyolysis occurs when muscle fibers break down and let proteins and other substances enter the bloodstream. Statin medications used to control cholesterol levels can cause rhabdomyolysis in rare cases. Mild muscle soreness is a potential side effect of statin therapy, but severe muscle pain may indicate muscle breakdown. Combination therapy of statins and niacin together can increase the risk of developing rhabdomyolysis.

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