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3. For Treating Leg Cramps

The neuromuscular junction has excitable nerve endings, which can lead to leg cramps, and for years doctors prescribed quinine as a treatment. The drug quells the constant nerve firing at the junction and increases the time between those uncomfortable spasms. While it was somewhat effective, there were numerous side effects, and the FDA banned its use for leg cramps in 2009.

leg cramps side effects Peter Dazeley / Getty Images

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