Understanding the Link Between High Potassium and Health

6. Addison's Disease

Addison’s disease affects the adrenal glands, which are responsible for producing hormones like aldosterone that help regulate sodium and potassium levels. When aldosterone levels drop too low, the kidneys struggle to eliminate potassium efficiently, leading to hyperkalemia. This hormonal imbalance can develop slowly over time or appear suddenly during an adrenal crisis, which is a medical emergency. Treating Addison’s disease with hormone replacement therapy typically restores potassium levels to a healthy range.