The early signs of beriberi include fatigue, irritability, loss of appetite, sleeping problems, memory loss, weight loss, and abdominal discomfort. People with dry beriberi complain of pain and cramps in the legs, along with muscle atrophy. Leg edema and lung congestion occur in those who have developed wet beriberi. If the deficiency is severe, additional symptoms may develop that affect the heart, nervous system, and brain.

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