Researchers have studied the antifungal qualities of tea tree oil. One 2013 study indicates the oil reduces Trichophyton rubrum, which can cause nail fungus and athlete's foot. In an earlier study, pure oil was as effective as an over-the-counter medication in treating toenail infections. Researchers also tried adding tea tree oil to a medical cream containing butenafine hydrochloride. The enhanced cream cured toenail fungus in 80 percent of test subjects.

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