Severe vitamin B3 deficiency can cause a disease known as pellagra. Symptoms of pellagra include skin inflammation or irritation, weak muscles, and digestive issues. This disease is also associated with alcoholism as well as malnutrition. Pellagra can be fatal within years if the vitamin B3 levels are not restored and maintained. Increasing the dosage of niacin supplements can help treat pellagra. Talk to your doctor about the benefits and risks of nicotinamide.

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