When your muscles are sore, you want to get relief as quickly as possible, and over-the-counter pain relievers can provide that relief. While most people choose non-steroidal anti-inflammatories (NSAIDs), these medications aren't as helpful as you might think. NSAIDs actually inhibit the production of muscle-healing prostaglandins and slow the process of muscle recovery. The best option is to choose a pain reliever that contains acetaminophen to gain temporary pain relief without interfering with your body's ability to heal itself.

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