Toxicity is very rare if naturally occurring vitamins in foods are the only source of folate in a person's diet. Fortified foods and vitamin supplements contain synthetic folic acid. The Institute of Medicine set the upper limit for folic acid intake at 1,000 mcg per day. People taking vitamin supplements may surpass 1,000 mcg daily due to the additional folic acid in fortified foods. Most adults only need approximately 400-500 mcg daily. Although folic acid can cause adverse effects, most people don't experience any side effects at all. Folic acid is water-soluble, so our bodies can excrete most of the excess through urine.

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