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6. Polycystic Ovary Syndrome

PCOS can cause your periods to become less frequent and very irregular. The symptoms generally show up at puberty, so many women never experience regular cycles. You can develop PCOS later in life, however, often as the result of weight gain. PCOS periods [MayoClinic] are often abnormally heavy and over 35 days apart.

A group of teen girls standing together. andreaortizg / Getty Images

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