Understanding and Managing Mpox (Monkeypox)

9. Vaccines

After shortages in 2022, vaccines for mpox are now commercially available, and the CDC recommends vaccination for anyone who is at higher risk of getting mpox or has had a recent exposure, including children. People who get vaccinated within four days of exposure may prevent the disease from developing, and getting vaccinated within 14 days of exposure can reduce the severity of the infection and the duration of the illness. Jynneos is a two-dose vaccine that is effective against all forms of the virus, but only a quarter of at-risk Americans received two doses by January 2023. The second dose is usually administered four weeks after the first dose, increasing protection.