Doctors often order an AST blood test as a part of a routine checkup or if someone complains of symptoms of liver damage. These symptoms can include fatigue, weakness, nausea, vomiting, jaundice, itching, or swelling in the ankles, legs, or abdomen.
A health care provider may also order AST and other blood tests for people with a family history of liver disease or those with obesity, diabetes, excessive alcohol use, or suspected or confirmed hepatitis.

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