A muscle can become tired and cramp up when overused. A nocturnal leg cramp that tightens up at night while lying still, for instance, could be due to a long period of inactivity or, ironically, overuse of a muscle. A lack of electrolytes, water, or other minerals can irritate muscles, which can also lead to spasms. When a muscle fails to receive adequate blood supply, contractions can occur when the muscles are suddenly asked to become active.
This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.