Currently, the U.S. Food and Drug Administration has not approved any medications specifically for disruptive mood dysregulation disorder. Because of this, experts use stimulants, antidepressants, and atypical antipsychotics to relieve the symptoms. Atypical antipsychotics can have serious side effects, however, and doctors will only use them when other methods fail. Antidepressants may increase suicidal thoughts and behaviors in young people, so caregivers and doctors will closely monitor any children prescribed these medications.

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