When you lose a lot of weight, you've usually been exercising and watching your diet. When the loss is too rapid, however, or when there's no obvious cause for it, it can be a sign of serious issues. Lymphoma-affected cells are energy hungry. So are the immune cells working to fight them off. Between the two of them, these cells can exhaust the body's fat reserves. This process happens at a much higher rate than normal activity does. Eventually, energy burned in this way leads to rapid drops in both body weight and fat composition. The warning sign for most people is a drop of 5 percent of your total body weight in a single month. Be especially wary if this is not caused by a change in diet or exercise patterns. Similarly, a 10-percent drop in six months is also a potential warning sign for lymphoma.

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