10 Signs of Lymphoma

3. Running a High Fever

High fevers are also a typical lymphoma sign. This is especially likely if the fever comes on at night. Like chills and hot flashes, fever is also a common symptom of less-concerning ailments. That means it's too early to leap to conclusions at the first temperature rise. Fever becomes a potential sign of lymphoma when it lingers beyond a few days without breaking. Ironically, high temperatures are less likely to be a sign of lymphoma. Persistent, low-grade fevers sometimes are an early sign of the disease. Lingering fever is a good reason to set an appointment to see a doctor.