There currently is no vaccine available in the U.S. to prevent hepatitis E, though there are vaccines that are under development in some parts of the world. The best prevention is good sanitation practices. Clean drinking water is imperative. For those who travel to areas of the world where HEV infections are prevalent, experts advise drinking only purified water. People in both developed and developing countries should avoid undercooked pork and be cautious when handling and preparing deer meat. Individuals who work closely with animals including veterinarians and butchers should take precautionary measures to prevent infection.

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