A study in the Journal of Bone and Joint Surgery suggests that urate crystals can rub against the joints, causing damage and possibly leading to fractures. These bone injuries do not necessarily take place in the area of the body where gout first appeared. In fact, the study noted examples of a foot fracture, patella fracture, and snapping of a prosthetic hip, all due to bones weakened by over-production of urate crystals.

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