Factor V Leiden is caused by coagulation of the blood that continues for longer than it should. Activated protein C (APC) is responsible for stopping the clotting action of F5, but this gene does not respond correctly in people with the genetic mutation associated with factor V Leiden. One or more other genetic mutations combined with F5 can further increase the risk of developing thrombosis.

This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.