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Familial adenomatous polyposis (FAP) is a genetic disease that causes colorectal cancer. In people with this gene mutation, thousands of non-cancerous polyps develop in the colon and rectum and eventually become malignant or cancerous. FAP cannot be cured, but surgical removal of the colon reduces the risk of colorectal cancer.

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1. Variations in Familial Adenomatous Polyposis

There are three variations of familial adenomatous polyposis: classic, attenuated, and autosomal. In attenuated FAP, polyp growth begins later in life and colorectal cancer typically does not occur until a person is in their fifties. Autosomal FAP is a more mild form causing significantly fewer polyps.

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