logo
Advertisement

Many common infections result from fungi, including ringworm, athlete's foot, and thrush. While most of these infections are common and easily treated in healthy people, fungal infections can lead to serious problems in those with weakened immune systems.

One fungus of immediate concern is Candida auris, which was first reported in Japan in 2009 and has since spread worldwide.

The Emergence of Candida Auris

The first case of Candida auris was reported in Japan in 2009, where it was found in a patient's ear. Since then, Candida auris infections have spread, with more than 1400 cases reported in the U.S. alone in 2021.

C. auris lives on the skin for a long time and as long as two weeks on surfaces in lab studies. People can have C. auris on their skin without getting sick. Still, because of its lifespan, they are at risk of developing an infection if their immune system becomes compromised soon after exposure.

A female doctor sits at her desk and chats to an elderly female patient while looking at her test results Lordn/ Getty Images

Advertisement

A Global Health Threat

There are a few reasons why Candida auris is concerning to the CDC and other agencies worldwide. C. auris is especially dangerous in hospital settings as it can easily infect those already sick. Identifying C. auris in a lab is challenging, which leads to delayed treatment.

Because it is often resistant to the majority of drugs, the fungus can be difficult to treat even when caught early.

Team of doctors and businessmen communicating while having a meeting at doctor's office in the hospital. skynesher/ Getty Images

Advertisement

Mortality Rate

Candida auris has a high mortality rate, mainly because of its drug resistance. Multiple strains are resistant to one or two available antifungal drug classes, but some are resistant to all three, leaving few treatment options. C. auris tends to occur in clusters in healthcare settings because it is easily transmissible, and hospitalized patients are particularly vulnerable.

Doctor consulting with senior male patient in hospital The Good Brigade/ Getty Images

Advertisement

How It Spreads

Candida auris is transmitted from person to person, which is different from other Candida species that typically arise from the person's own flora. C. auris thrives on the skin, particularly in the groin and armpits, and can colonize someone within days of exposure.

In addition to acquiring C. auris from another person, people can also get it from surfaces. It has been found in patients' rooms and on objects like chairs, blood pressure cuffs, pumps, ventilators, and beds. This fungus can survive on surfaces for as long as four weeks, making it easy to spread.

An unrecognizable female patient wears a hospital gown and sits on the edge of the hospital bed. SDI Productions/ Getty Images

Advertisement

Symptoms

Symptoms of a Candida auris infection are similar to those of other fungal infections. It can colonize various areas of the body, including the nose, lungs, heart, liver, vagina, skin, ears, brain, and wounds. The most common symptoms are fever and chills that don't improve after antibiotics, though a person with a C. auris infection may develop a urinary tract infection, skin abscess, ear infection, or meningitis.

Sick young woman headache fever cough cold sneezing sitting under the blanket on sofa in living room at home. Healthcare concept. Phiromya Intawongpan/ Getty Images

Advertisement

Risk Factors

Risk factors for developing a Candida auris infection are similar to other Candida infections. People with diabetes mellitus, HIV, or cancer or who have received chemotherapy, hemodialysis, corticosteroids, a blood transfusion, or a transplant are at risk, as are those with an indwelling urinary catheter or central venous catheter.

People in the ICU or who have had surgery within 30 days are also more likely to develop a C. auris infection.

Hospital Ward: Friendly Head Nurse Talks with Elderly Patient Resting in Bed. gorodenkoff/ Getty Images

Advertisement

Medication

Drug resistance is the most challenging aspect of treating a Candida auris infection. One study showed that 25 percent of infections were resistant to multiple drugs. There is no standard treatment, and most cases are managed on a case-by-case basis according to susceptibility testing.

The CDC has put together tentative guidelines but recommends close monitoring for clinical improvement and repeating susceptibility testing to asses for drug resistance.

Good-looking elderly female nutrition expert sitting in living-room at table using laptop, holding bottle shurkin_son/ Getty Images

Advertisement

Other Treatment Approaches

There are some treatment approaches in addition to antifungal medications. Once a doctor detects the infection, they remove any central venous catheters, urinary catheters, or other drains from the patient. If antifungal medication appears ineffective, doctors should monitor the patient for complications from the infection spreading, including endocarditis, abscesses, and eye problems.

The Infectious Disease Society of America indicates that patients should continue taking antifungal medication for two weeks, even if the cultures come back negative after the treatment.

Smiling senior woman sitting on hospital bed listening to mature surgeon at private clinic. Ridofranz/ Getty Images

Advertisement

Prevention

Because they are so hard to treat, preventing Candida auris infections is essential. The best way to do so is to reduce the number of locations the fungus can enter the body. This means healthcare practitioners should be focused on keeping catheters and tracheostomy sites clean and well-maintained. Patients who have lines and tubes into their bodies should have these removed as soon as they are no longer needed.

 American nurse at the hospital checking the vitals on a hospitalized patient - healthcare and medicine concepts. andresr/ Getty Images

Advertisement

Complications

Complications of Candida auris depend on the location and extent of the infection. Localized infections can lead to significant complications if they get into the bloodstream because once the fugus is in the bloodstream, it can spread throughout the body and eventually lead to multi-system organ failure.

In some cases, C. auris infections that spread via the blood become fatal.

Young girl holds the hand of her ill grandmother Justin Paget/ Getty Images

Advertisement

Popular Now on Facty Health


Disclaimer

This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.