Speaking of joint pain, this is the primary symptom in adults with fifth disease. It is most common in the wrists, knees, and ankles. These painful inconveniences tend to go away after about two weeks. However, around 10 percent of adults who contract the virus will suffer from prolonged, sometimes chronic, joint pain and other related fifth disease symptoms. Muscle and abdominal pain is another familiar ache as a result of the infection. They also tend to suffer from flu-like problems, but on a more severe level. A headache, sore throat, and fever may have you in bed for some time. At least adults seldom develop a rash in association with fifth disease, but they may have the severe symptoms for seven to ten days.

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