Anorexia can cause problems with the heart and circulation, including leaking heart valves, low blood pressure, and abnormal heart rhythms. Additionally, as the body loses muscle mass, it loses heart muscle at a preferential rate, so the heart gets smaller and weaker. It gets worse at increasing circulation in response to exercise, and pulse and blood pressure drop. The cardiac toll is acute, significant, and sets in quickly. Heart damage is the most common reason for hospitalization in people with anorexia.

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