Fecal matter exits the body through the rectum. Bleeding from this area is always concerning. Rectal bleeding can present with or without pain, and the blood may be seen in the stool or separate and may be noted when wiping. This sign can indicate infection or other serious colon problems. In some cases of diverticulitis, blood in the diverticula causes ruptures, which lead to severe pain, infection, and blood passed with stools.

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