Similar to symptoms of a peptic ulcer, ZES symptoms begin as dull pain or burning sensations between the mid-chest and naval. Discomfort usually happens on an empty stomach, and eating food may or may not relieve pain or burning. Other signs of ZES include:
Symptoms vary among people with ZES. Some report only diarrhea, while others experience a severe acid indigestion condition called GERD or gastroesophageal reflux disorder.

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