Certain groups are more likely to develop Barrett’s esophagus, with the highest risk seen in men, non-Hispanic whites, and individuals over age 50. Smoking and obesity are also significant risk factors, as both can aggravate acid reflux, a key contributor to the condition. A family history of Barrett’s esophagus or esophageal cancer further increases susceptibility. For those with at least three risk factors, screening with an endoscopy is strongly recommended to catch potential changes early. While women are generally less likely to develop Barrett’s esophagus, those with uncontrolled reflux or other concerning symptoms should still consider screening to address potential risks.

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