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2. Abdominal Pain and Cramping

Ulcerative colitis causes abdominal pain akin to cramping, due to inflammation of the large intestine or colon lining. The overlying muscles become tense and sore. The pain ranges from mild to severe and tends to cease as diarrhea subsides. Experts often recommend avoiding NSAIDs intended to ease stomach pain and instead take antispasmodic medication under the supervision of a physician.

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