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Reye's syndrome or RS is a progressive disorder characterized by brain and liver damage. RS causes massive deposits of fat in the liver and other organs. The Australian pathologist Douglas Reye produced the first detailed analysis of Reye syndrome in 1963. RS affects fewer than one in a million children each year and is almost never seen in adults. Those who do develop Reye's syndrome tend to experience very mild symptoms with complete recovery. However, the disorder can be fatal or cause long-term difficulties for children and adolescents.

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1. Stage One of Reye's Syndrome

Reye's syndrome follows a progression of five stages over several hours or days. The first symptoms are vomiting and irritability, followed by a  rash on the palms of the hands and soles of the feet, confusion, headache, combativeness, or lack of energy. Vomiting quickly becomes persistent and severe, even if the child is not eating or drinking anything.

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