A doctor can often diagnose Henoch-Schonlein purpura on the basis of a physical exam and a thorough history of the symptoms. If additional diagnostic testing is necessary, the patient may require a skin biopsy or urinalysis. The tissue collected in a skin biopsy reveals antibody deposits on the skin. A urinalysis can detect hematuria or proteinuria - blood or excess protein, respectively - in the urine. If the doctor suspects the kidneys are affected, he or she may call for a kidney biopsy.

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