Each year, an individual’s risk of developing a more serious condition increases by one percent. In other words, someone who has lived with monoclonal gammopathy for ten years has a ten percent risk of disease progression. In addition to multiple myeloma—one of the more common complications—monoclonal gammopathy can lead to Waldenstrom macroglobulinemia, lymphoma, light chain amyloidosis, or Bence Jones proteinuria. Other complications include blood clots, kidney problems, and bone fractures.

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