Blood is an essential fluid that performs many functions, such as transporting oxygen and providing nutrients to cells. Continuously made in the body, this red liquid consists of several components: plasma, platelets, red blood cells, and white blood cells. Various blood disorders can affect this life-giving system, including anemia, sickle cell disease, and leukemia. Rarely, a person will develop an abnormal protein in the blood—this condition is monoclonal gammopathy.
Monoclonal gammopathy (MGUS) is a rare condition that produces an abnormal protein—an M-protein—in the blood. Different subtypes include IgA-MGUS, IgM-MGUS, IgE-MGUS, IgG-MGUS, and IgD-MGUS. While it usually causes no problems, in some cases monoclonal gammopathy can lead to various cancers such as lymphoma or multiple myeloma over time. For this reason, most cases require close monitoring or regular checkups.
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