The best way to treat cutaneous porphyrias is to prevent them. People who know they are at risk can avoid sun exposure and receive regular blood draws to reduce the heme iron in the body. Some medications also reduce the production of porphyrins. People with erythropoietic protoporphyria may require a bone marrow transplant to successfully cure the disease, and any type of cutaneous porphyria can require a liver transplant if the condition becomes severe.

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