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Leukocytoclastic vasculitis or hypersensitivity vasculitis is a condition involving inflammation of small blood vessels. The symptoms and risks of leukocytoclastic vasculitis are well-known, although the specific disease process is not fully understood. The main characteristic of leukocytoclastic vasculitis, commonly referred to as LCV, is leukocytoclasis, damage within blood vessels due to debris left by neutrophils, a type of immune cell. This condition may be acute or chronic. Chronic LCV can develop in the skin or kidneys, central nervous system, heart, lungs, or gastrointestinal tract.

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1. Acute LCV

LCV on the skin presents as dark red or slightly purple raised lesions. Blood vessels in the skin leak and cause dark bruises. Several lesions together often affect the legs and buttocks and are less common on upper limbs. Lesions may be painful and itchy but can also be asymptomatic.

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